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C.10. You decide to use rotational thromboelastometry (ROTEM) to guide your resuscitation efforts. After 20 minutes, the results of the ROTEM are normal; however, the field is still bloody. The surgeon suggests tranexamic acid (TXA) for the patient. What is TXA and what is its mechanism of action? Is TXA effective at reducing blood loss in major spine surgery? What are the risks of TXA administration? Is TXA an appropriate choice in this patient? i

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