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The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs
Tapering Antidepressants in Practice
Table of Contents
Free Topics
Abbreviations List
About
Adverse Effects of Antidepressants
Discussing Deprescribing Gabapentinoids
Flowchart - An Overview of the Process of Tapering Antidepressants
Flowchart - An Overview of the Process of Tapering Psychiatric Drugs
Mis-Diagnosis of Withdrawal Effects As Relapse
Notes on Using The Maudsley Deprescribing Guidelines
Other Considerations in Tapering Benzodiazepines and Z-Drugs
Other Considerations in Tapering Gabapentinoids
Physical Dependence vs Addiction in Use of Benzodiazepines and Z-Drugs
Preface
Recent Developments in the Understanding of Antidepressant Withdrawal
Tapering Benzodiazepines and Z-Drugs in Practice
Tapering Gabapentinoids in Practice
When and Why to Stop Gabapentinoids
Chapter 1 Introduction to Deprescribing Psychiatric Medications
Deprescribing As an Intervention
Barriers and Facilitators to Deprescribing
Deprescribing As an Intervention
The Context for Deprescribing
Why Deprescribe?
How to Deprescribe Psychiatric Medications Safely
Further Topics
How to Deprescribe Psychiatric Medications Safely
Practical Options for Prescribing Gradually Tapering Doses
Psychological Aspects of Tapering
Tapering Psychiatric Drugs in Practice
The Neurobiology of Tapering
Withdrawal Effects from Psychiatric Medications
Clinical Aspects of Psychiatric Drug Withdrawal
Mis-Diagnosis of Withdrawal Effects As Relapse
Pathophysiology of Psychiatric Drug Withdrawal Symptoms
Specific Issues in Psychiatric Drug Withdrawal
Withdrawal Effects from Psychiatric Medications
Chapter 2 Safe Deprescribing of Antidepressants
How to Deprescribe Antidepressants Safely
How to Deprescribe Antidepressants Safely
Hyperbolic Tapering of Antidepressants
Managing Complications of Antidepressant Discontinuation
Practical Options in Prescribing Gradually Tapering Doses of Antidepressants
Psychological Aspects of Antidepressant Tapering
Tapering Antidepressants Gradually
Tapering Antidepressants in Practice
Tapering Guidance for Specific Antidepressants
Agomelatine
Amitriptyline
Bupropion
Citalopram
Clomipramine
Desvenlafaxine
Dosulepin
Doxepin
Duloxetine
Escitalopram
Fluoxetine
Fluvoxamine
Imipramine
Lofepramine
Mirtazapine
Moclobemide
Nortriptyline
Paroxetine
Phenelzine
Sertraline
Tapering Guidance for Specific Antidepressants
Tranylcypromine
Trazodone
Venlafaxine
Vilazodone
Vortioxetine
When and Why to Stop Antidepressants
Adverse Effects of Antidepressants
Discussing Deprescribing Antidepressants with Patients
When and Why to Stop Antidepressants
Withdrawal Effects from Antidepressants
Clinical Aspects of Antidepressant Withdrawal
Distinguishing Antidepressant Withdrawal Symptoms from New Onset of a Physical or Mental Health Condition
Distinguishing Antidepressant Withdrawal Symptoms from Relapse
Factors Influencing Development of Withdrawal Effects
How Common, Severe and Long-Lasting are Withdrawal Symptoms from Antidepressants?
Pathophysiology of Antidepressant Withdrawal Symptoms
Post-SSRI Sexual Dysfunction
Protracted Antidepressant Withdrawal Syndrome
Recent Developments in the Understanding of Antidepressant Withdrawal
Stratfiying Risk of Antidepressant Withdrawal
Withdrawal Symptoms During Antidepressant Maintenance Treatment or Switching Medication
Chapter 3 Safe Deprescribing of Benzodiazepines and Z-drugs
How to Deprescribe Benzodiazepines and Z-Drugs Safely
How to Deprescribe Benzodiazepines and Z-Drugs Safely
Hyperbolic Tapering of Benzodiazepines and Z-Drugs
Making Up Smaller Doses of Benzodiazepines and Z-Drugs Practically
Management of Complications of Benzodiazepine and Z-Drug Discontinuation
Other Considerations in Tapering Benzodiazepines and Z-Drugs
Psychological Aspects of Tapering Benzodiazepines and Z-Drugs
Switching to Longer-Acting Benzodiazepines to Taper
Tapering Benzodiazepines and Z-Drugs Gradually
Tapering Benzodiazepines and Z-Drugs in Practice
Tapering Guidance for Specific Benzodiazepines and Z-Drugs
Alprazolam
Buspirone
Chlordiazepoxide
Clonazepam
Clorazepate
Diazepam
Estazolam
Eszopiclone
Flurazepam
Lorazepam
Lormetazepam
Nitrazepam
Oxazepam
Quazepam
Tapering Guidance for Specific Benzodiazepines and Z-Drugs
Temazepam
Triazolam
Zaleplon
Zolpidem
Zopiclone
When and Why to Stop Benzodiazepines and Z-Drugs
Discussing Deprescribing Benzodiazepines and Z-Drugs
When and Why to Stop Benzodiazepines and Z-Drugs
Withdrawal Symptoms from Benzodiazepines and Z-Drugs
Distinguishing Benzodiazepine Withdrawal Symptoms from Return of an Underlying Condition
Pathophysiology of Benzodiazepine Withdrawal Syndrome
Physical Dependence vs Addiction in Use of Benzodiazepines and Z-Drugs
Protracted Benzodiazepine Withdrawal Syndrome
Variety of Withdrawal Symptoms from Benzodiazepines and Z-Drugs
Withdrawal Symptoms During Benzodiazepine Maintenance Treatment
Withdrawal Symptoms from Benzodiazepines and Z-Drugs
Chapter 4 Safe Deprescribing of Gabapentinoids
How to Deprescribe Gabapentinoids Safely
Making Up Smaller Doses of Gabapentinoids Practically
Management of Complications of Gabapentinoid Discontinuation
Other Considerations in Tapering Gabapentinoids
Principles for Tapering Gabapentinoids
Psychological Aspects of Tapering Gabapentinoids
Tapering Gabapentinoids in Practice
Overview of Gabapentinoid Withdrawal Effects
Overview of Gabapentinoid Withdrawal Effects
Physical Dependence vs Addiction in Use of Gabapentinoids
Tapering Guidance for Specific Gabapentinoids
Gabapentin
Pregabalin
Tapering Guidance for Specific Gabapentinoids
When and Why to Stop Gabapentinoids
Discussing Deprescribing Gabapentinoids
When and Why to Stop Gabapentinoids
Front Matter
Abbreviations List
Notes on Using The Maudsley Deprescribing Guidelines
Preface
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