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The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs
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Nitrazepam
Nitrazepam
Switching to Longer-Acting Benzodiazepines to Taper
N-methyl-d-aspartate (NMDA)
Nocebo effects
How Common, Severe and Long-Lasting are Withdrawal Symptoms from Antidepressants?
Pathophysiology of Antidepressant Withdrawal Symptoms
Noradrenaline
Clinical Aspects of Antidepressant Withdrawal
Hyperbolic Tapering of Antidepressants
Recent Developments in the Understanding of Antidepressant Withdrawal
Nortriptyline
Nutritional supplements
Other Considerations in Tapering Benzodiazepines and Z-Drugs
Other Considerations in Tapering Gabapentinoids
obsessive compulsive disorders (OCD)
Adverse Effects of Antidepressants
When and Why to Stop Antidepressants
When and Why to Stop Gabapentinoids
Off-licence/off-label options for tapering
antidepressants
benzodiazepines and z-drugs
gabapentinoids
Practical Options for Prescribing Gradually Tapering Doses
Opening capsules to count/weigh beads
Practical Options for Prescribing Gradually Tapering Doses
Practical Options in Prescribing Gradually Tapering Doses of Antidepressants
Over-prescription aspects
Oxazepam
Oxazepam
Switching to Longer-Acting Benzodiazepines to Taper
Pain
Protracted Benzodiazepine Withdrawal Syndrome
Tapering Gabapentinoids in Practice
Variety of Withdrawal Symptoms from Benzodiazepines and Z-Drugs
When and Why to Stop Gabapentinoids
Panic disorders
antidepressants
benzodiazepines and z-drugs
Paroxetine
Clinical Aspects of Antidepressant Withdrawal
Factors Influencing Development of Withdrawal Effects
Hyperbolic Tapering of Antidepressants
Paroxetine
Stratfiying Risk of Antidepressant Withdrawal
Tapering Antidepressants Gradually
Pathogenesis, withdrawal effects/ symptoms
Hyperbolic Tapering of Antidepressants
Pathophysiology of Antidepressant Withdrawal Symptoms
Pathophysiology of Benzodiazepine Withdrawal Syndrome
The Neurobiology of Tapering
Pathophysiology
antidepressants
benzodiazepines and z-drugs
gabapentinoids
Pathophysiology of Psychiatric Drug Withdrawal Symptoms
Specific Issues in Psychiatric Drug Withdrawal
Patient perceptions/preferences
antidepressants
benzodiazepines and z-drugs
Clinical Aspects of Psychiatric Drug Withdrawal
gabapentinoids
knowledge and advocacy
Psychological Aspects of Tapering
The Context for Deprescribing
Why Deprescribe?
Pharmacology
antidepressants
benzodiazepines and z-drugs
Further Topics
gabapentinoids
How to Deprescribe Psychiatric Medications Safely
Mis-Diagnosis of Withdrawal Effects As Relapse
The Context for Deprescribing
The Neurobiology of Tapering
When and Why to Stop Antidepressants
Phenelzine
Physical dependence
antidepressants
benzodiazepines and z-drugs
gabapentinoids
Mis-Diagnosis of Withdrawal Effects As Relapse
Pathophysiology of Psychiatric Drug Withdrawal Symptoms
Physiological factors in withdrawal
antidepressants
Barriers and Facilitators to Deprescribing
benzodiazepines
gabapentinoids
Mis-Diagnosis of Withdrawal Effects As Relapse
Pathophysiology of Psychiatric Drug Withdrawal Symptoms
Psychological Aspects of Tapering
Specific Issues in Psychiatric Drug Withdrawal
Polypharmacy
Deprescribing As an Intervention
Discussing Deprescribing Gabapentinoids
Tapering Gabapentinoids in Practice
Tapering Psychiatric Drugs in Practice
Why Deprescribe?
post-SSRI sexual dysfunction (PSSD)
Adverse Effects of Antidepressants
Managing Complications of Antidepressant Discontinuation
Post-SSRI Sexual Dysfunction
Post tapering aspects
Tapering Benzodiazepines and Z-Drugs in Practice
Tapering Gabapentinoids in Practice
post-traumatic stress disorders (PTSD)
When and Why to Stop Antidepressants
When and Why to Stop Gabapentinoids
Practical tapering options
antidepressants
benzodiazepines and z-drugs
gabapentinoids
Practical Options for Prescribing Gradually Tapering Doses
Tapering Psychiatric Drugs in Practice
Pregabalin
Making Up Smaller Doses of Gabapentinoids Practically
Pregabalin
Principles for Tapering Gabapentinoids
Tapering Guidance for Specific Gabapentinoids
When and Why to Stop Gabapentinoids
Pre-medication aspects
Switching to Longer-Acting Benzodiazepines to Taper
When and Why to Stop Benzodiazepines and Z-Drugs
Preparation for deprescribing
benzodiazepines and z-drugs
gabapentinoids
Prolonged/protracted withdrawal syndrome
antidepressants
benzodiazepines and z-drugs
Further Topics
Specific Issues in Psychiatric Drug Withdrawal
Tapering Psychiatric Drugs in Practice
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