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The Maudsley Prescribing Guidelines in Psychiatry
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Lack of engagement with psychological therapies
Lamotrigine
borderline personality disorder
in overdose
restarting after period of non-compliance
clozapine augmentation
life-threatening cutaneous reactions
target range
Laxative misuse/abuse
Biochemical and haematological effects of psychotropics
Eating disorders
Laxatives
Acting on clozapine plasma concentration results
Clozapine-induced gastrointestinal hypomotility
Safer prescribing for physical conditions in dementia
Clozapine: common adverse effects
Initiation of clozapine in the community
Learning difficulties
epilepsy comorbidity
Learning disabilities
capacity and consent
general considerations
prescribing practice
Legal issues
Lemborexant
managing sleep disturbance in dementia
in overdose
use in patients with hepatic impairment
Less commonly used treatments, well supported by published evidence (no preference implied by order)
Levetiracetam, for tardive dyskinesia
Levomepromazine
Relative adverse effects - a rough guide
Quick reference for licensed maximum doses
Lewy body dementia
Parkinson's disease
Dementia
Licensed maximum doses of antipsychotics, according to US Food and Drug Administration labelling, where available
Linear dose reductions of olanzapine cause increasingly large reductions in D2 dopaminergic receptor blockade.
Linear reductions of dose cause increasingly large reductions in effect on receptor targets, probably associated with more withdrawal effects.
Liraglutide, for antipsychotic-induced weight gain
Lisdexamfetamine
borderline personality disorder
attention deficit hyperactivity disorder in adults
bulimia nervosa/binge eating disorder
Lithium: clinically relevant drug interactions
Lithium plasma levels
Lithium
liver function tests (LFTs)
monitoring to access drug effects
interpretation
Lofexidine, clozapine-induced hypersalivation
long-acting injectable (LAI)
Long-acting oral antipsychotics
improving adherence
restarting after period of non-compliance
preventing sudden cessation
Loperamide, safety in older patients/dementia
Lactate in blood, psychotropic agent effects
Leukopenia, psychotropic agent effects
Libido
Linaclotide, for constipation treatment
Linear reductions of dose cause increasingly large reductions in effect on GABA-A receptor occupancy.
Lipoproteins in blood, psychotropic agent effects
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