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TNM Cancer Staging System
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Five-year overall survival of 6,127 patients with local MCC only (clinically and, if known, pathologically node negative) in the NCDB, stratified by T category ( 2 cm, T1; 2 cm, T2/3; involving fascia, muscle, cartilage, or bone, T4)
For appendicular skeleton, trunk, skull, and facial bones, T1 is defined as tumor 8 cm or less in greatest dimension
For carcinomas T2 is tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus
For carcinomas T4 is tumor invading the bladder mucosa and/or bowel mucosa (bullous edema is not sufficient to classify a tumor as T4)
For appendicular skeleton, trunk, skull, and facial bones, T3 is defined as discontinuous tumors in the primary bone site
For carcinomas T1b is tumor invading one half or more of the myometrium
For carcinomas T3a is tumor involving the serosa and/or adnexa (direct extension or metastasis)
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