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Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs
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dacarbazine (DTIC)
Triazines (Three Attached Nitrogen Atoms)
Alkylating Agents
DCIS
dCTP
deep venous thrombosis (DVT)
dehydrogenase (DPD)
deoxycytidine kinase (DCK)
deoxynucleotide triphosphates (dNTPs)
Answer 3.7
Ribonucleotide Reductase (RNR) is Responsible for Synthesizing Deoxyribonucleotides
deoxythymidine monophosphate (dTMP)
Folic Acid Cycle as Relevant for Conversion of Deoxyuridine Monophosphate (dUMP)
Pyrimidine Analogs
Mechanism of Leucovorin (LV) "Rescue" in High-Dose Methotrexate (MTX)
DFHR
DHEA
DHT
differentiation syndrome (DS)
Differentiating Agents and Microenvironment
Answer 8.2
Question 8.2
diffuse, large B cell lymphoma (DLBCL)
dihydrofolate reductase (DFHR)
Answer 3.7
Question 4.5
Antimetabolites: Hydroxyurea, Pyrimidine and Purine Analogs, and L-Asparaginase
disease-free survival (DFS)
Answer 16.5
Basic Drug Development With Structural Considerations
DLBCL
DNA damage response (DRR)
DNA-PK targeting
PARP inhibitors
DNA Repair, Apoptotic Pathways, CDK Inhibitors
DNA repair
overview
risk and intensity
DNA structure
dNTPs
dose-escalation limiting toxicity (DLT)
DPD
DRR
Drug approval and regulatory issues
dose refinement studies
food effect
INDâchr(128)”enabling nonclinical studies for cancer drugs
additional pharmacology considerations
drug-drug interaction
hepatic impairment
QT prolongation
renal impairment
recommended phase 2 dose (RP2D)
DAMPA
DCK
DDB1
dehydroepiand rosterone (DHEA)
de novo synthesis of thymidine monophosphate (dTMP)
deoxycytidine triphosphate (dCTP)
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