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Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs
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Mabs
prostate cancer
17α-hydroxylase/17-lyase (CYP17) inhibitors
and rogen deprivation therapy
apalutamide
darolutamide
GnRH agonists and antagonists
schematic structure of GnRH agonist relative to native GnRH
treatment goal
abiraterone and its prodrug, abiraterone acetate
and rogen receptor (AR) activation by dihydrotestosterone (DHT)
AR antagonists (antiand rogens)
enzalutamide
overview
steroidal and nonsteroidal antiand rogens
mammalian target of rapamycin (mTOR)
Transplant-Related Agents
Hormonal Therapies Alone and in Combinations for Treatment of Breast Cancer
mantle cell lymphoma (MCL)
DNA Repair, Apoptotic Pathways, CDK Inhibitors
Answer 11.5
Targeted Therapies (Small Molecules)
MAPK
marginal zone lymphoma (MZL)
Targeted Therapies (Small Molecules)
Answer 11.5
maximal tolerated dose (MTD)
Drug Approval and Regulatory Issues
Answer 16.1
Question 16.2
maximum plasma concentration (Cmax)
MDR
MDSs
melphalan (Mel)
MESNA
methotrexate (MTX)
Answer 4.1
Answer 4.3
Antimetabolites: Antifolates
Question 4.3
Question 4.5
Answer 4.2
Answer 4.5
Question 4.2
Question 4.4
MGMT
minimal residual disease (MRD)
Answer 13.1
Immunotherapeutics Including Vaccines, Bispecifics, CAR-T, and Checkpoint Inhibitors
mismatch repair deficiency (MMRd)
MM
MMF
molecular pharmacological audit trial (MoPhAT)
monoclonal antibodies (Mabs)
class and target
Monoclonal Antibodies Including Immunoconjugates and Cytokine-Directed Agents
naked
prevention and management of infusion-related reactions
radioimmunoconjugates
uses
Answer 12.1
drug conjugates
Multiple Myeloma as a Paradigm for Multi-Targeted Intervention
overview
Question 12.1
structure and classification
MoPhAT
MPN
MRP
MTD
mTORC1
MTX
multidrug-resistant protein (MRP)
mycophenolate mofetil (MMF)
myelodysplastic syndromes (MDSs)
MAC
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