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Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs
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MAC
prostate cancer
abiraterone and its prodrug, abiraterone acetate
and rogen receptor (AR) activation by dihydrotestosterone (DHT)
AR antagonists (antiand rogens)
enzalutamide
overview
steroidal and nonsteroidal antiand rogens
17α-hydroxylase/17-lyase (CYP17) inhibitors
and rogen deprivation therapy
apalutamide
darolutamide
GnRH agonists and antagonists
schematic structure of GnRH agonist relative to native GnRH
treatment goal
mammalian target of rapamycin (mTOR)
Hormonal Therapies Alone and in Combinations for Treatment of Breast Cancer
Transplant-Related Agents
mantle cell lymphoma (MCL)
Answer 11.5
Targeted Therapies (Small Molecules)
DNA Repair, Apoptotic Pathways, CDK Inhibitors
marginal zone lymphoma (MZL)
Answer 11.5
Targeted Therapies (Small Molecules)
maximal tolerated dose (MTD)
Answer 16.1
Question 16.2
Drug Approval and Regulatory Issues
MCL
MDSCs
Mel
membrane attack complex (MAC)
Me-THF
methotrexate (MTX)
Answer 4.2
Answer 4.5
Question 4.2
Question 4.4
Answer 4.1
Answer 4.3
Antimetabolites: Antifolates
Question 4.3
Question 4.5
methylenetetrahydrofolate (Me-THF)
microsatellite instability (MSI)
minimal residual disease (MRD)
Immunotherapeutics Including Vaccines, Bispecifics, CAR-T, and Checkpoint Inhibitors
Answer 13.1
mitogen-activated protein kinase (MAPK)
Mabs
MAPK
maximum plasma concentration (Cmax)
MDR
MDSs
melphalan (Mel)
MESNA
MGMT
mismatch repair deficiency (MMRd)
MM
MMF
molecular pharmacological audit trial (MoPhAT)
monoclonal antibodies (Mabs)
class and target
Monoclonal Antibodies Including Immunoconjugates and Cytokine-Directed Agents
naked
prevention and management of infusion-related reactions
radioimmunoconjugates
uses
Answer 12.1
drug conjugates
Multiple Myeloma as a Paradigm for Multi-Targeted Intervention
overview
Question 12.1
structure and classification
MoPhAT
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