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TNM Cancer Staging System
Non-Hodgkin Lymphoma: Diffuse Large B-Cell Lymphoma
Table of Contents
Free Topics
103. Non-Hodgkin Lymphoma: Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
105. Non-Hodgkin Lymphoma: Diffuse Large B-Cell Lymphoma
111. Other Plasma Cell Disorders
14. Nasal Cavity and Ethmoid Sinus
20. Cutaneous Carcinoma of the Head and Neck
22. Esophagus and Esophagogastric Junction: Adenocarcinoma
29. Anus
30. Liver
34. Distal Bile Duct
36. Exocrine Pancreas
42. Neuroendocrine Tumors of the Pancreas
46. Bone: Appendicular Skeleton, Trunk, Skull and Facial Bones
52. Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs
64. Cervix Uteri
68. Ovary, Fallopian Tube, and Primary Peritoneal Carcinoma
8. Oral Cavity
82. Eyelid Carcinoma
86. Uvea: Iris Melanomas
93. Thyroid: Anaplastic
95. Parathyroid
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Cutaneous Carcinoma of the Head and Neck
Esophagus and Esophagogastric Junction: Adenocarcinoma
Nasal Cavity and Ethmoid Sinus
Oral Cavity
Part I: General Information on Cancer Staging and End-Results Reporting
1. Principles of Cancer Staging
1. Principles of Cancer Staging
Additional Staging Descriptors and Guidelines
AJCC Prognostic Stage Groups
AJCC TNM Staging System: Classifications, Categories and Rules for Staging
General Staging Rules
Introduction and Overview
Stage Classifications
2. Organization of the AJCC Cancer Staging Manual
2. Organization of the AJCC Cancer Staging Manual
Cancer Staging Data Form
Developing the 8th Edition Project Plan
New for This Edition
Organization of AJCC Cancer Staging Content
Vision for the AJCC Cancer Staging Manual, 8th Edition
3. Cancer Survival Analysis
3. Cancer Survival Analysis
Basic Concepts
Bibliography
Cause-Adjusted Survival
Comparison of Survival between Patient Groups
Competing Risks/Cumulative Incidence
Introduction
Patient-, Disease-, and Treatment-Specific Survival
Relative Survival
Standard Error of a Survival Estimate
Summary
The Kaplan-Meier Method
The Life Table Method
4. Risk Models for Individualized Prognosis in the Practice of Precision Oncology
4. Risk Models for Individualized Prognosis in the Practice of Precision Oncology
Acknowledgments
Background
Bibliography
Considerations for Use of Prognostication Models
Endorsement of Prognostication Models Meeting AJCC Criteria
Establishing Endorsement Criteria for Prognostication Models
Search Strategy for Prognostication Tools
The Evaluation Process
Part II: Head and Neck
5. Staging Head and Neck Cancers
10. Nasopharynx
11. HPV-Mediated (p16+) Oropharyngeal Cancer
12. Oropharynx (p16-)
13. Hypopharynx
14. Nasal Cavity and Ethmoid Sinus
15. Larynx: Supraglottis
16. Larynx: Glottis
17. Larynx: Subglottis
18. Larynx: Not Otherwise Specified
19. Mucosal Melanoma of the Head and Neck
20. Cutaneous Carcinoma of the Head and Neck
5. Staging Head and Neck Cancers
6. Cervical Lymph Nodes and Unknown Primary Tumors of the Head and Neck
7-A. Lip and Oral Cavity
8. Oral Cavity
9. Major Salivary Glands
Bibliography
Collection of Key Patient and Tumor Factors
Distant Metastases
Introduction and Overview of Key Concepts
Key Changes to Head and Neck Cancer Staging
Principles of Staging
Regional Lymph Nodes
Survival Data
Part III: Upper Gastrointestinal Tract
21. Esophagus and Esophagogastric Junction: Squamous Cell Carcinoma
22. Esophagus and Esophagogastric Junction: Adenocarcinoma
23. Esophagus and Esophagogastric Junction: Other Histologies
24. Stomach
25. Small Intestine: Adenocarcinoma
26. Small Intestine: Other Histologies
Part IV: Lower Gastrointestinal Tract
27. Appendix: Carcinoma
28. Colon and Rectum
29. Anus
Part V: Hepatobiliary System
30. Liver
31. Intrahepatic Bile Ducts
32. Gallbladder
33. Perihilar Bile Ducts
34. Distal Bile Duct
35. Ampulla of Vater
36. Exocrine Pancreas
Part VI: Neuroendocrine Tumors
37. Neuroendocrine Tumors of the Stomach
38. Neuroendocrine Tumors of the Duodenum and Ampulla of Vater
39. Neuroendocrine Tumors of the Jejunum and Ileum
40. Neuroendocrine Tumors of the Appendix
41. Neuroendocrine Tumors of the Colon and Rectum
42. Neuroendocrine Tumors of the Pancreas
Part VII: Thorax
43. Thymus
44. Lung
45. Malignant Pleural Mesothelioma
Part VIII: Bone
46. Bone: Appendicular Skeleton, Trunk, Skull and Facial Bones
47. Bone: Spine
48. Bone: Pelvis
Part IX: Soft Tissue Sarcoma
49. Introduction to Soft Tissue Sarcoma
50. Soft Tissue Sarcoma of the Head and Neck
51. Soft Tissue Sarcoma of the Trunk and Extremities
52. Soft Tissue Sarcoma of the Abdomen and Thoracic Visceral Organs
53. Gastrointestinal Stromal Tumor: Gastric and Omental
54. Gastrointestinal Stromal Tumor: Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal
55. Soft Tissue Sarcoma of the Retroperitoneum
56. Soft Tissue Sarcoma Unusual Histologies and Sites
Part X: Skin
57. Merkel Cell Carcinoma
58. Melanoma of the Skin
Part XI: Breast
59. Breast
60. Breast: Ductal Carcinoma in situ
Part XII: Female Reproductive Organs
61. Introduction to Female Reproductive Organs
61. Introduction to Female Reproductive Organs
62. Vulva
63. Vagina
64. Cervix Uteri
65. Corpus Uteri: Carcinoma and Carcinosarcoma
66. Corpus Uteri: Adenosarcoma
67. Corpus Uteri: Leiomyosarcoma and Endometrial Stromal Sarcoma
68. Ovary, Fallopian Tube, and Primary Peritoneal Carcinoma
69. Gestational Trophoblastic Neoplasms
Introduction
Part XIII: Male Genital Organs
70. Penis
71. Prostate
72. Testis
Part XIV: Urinary Tract
73. Kidney
74. Renal Pelvis and Ureter: Squamous Cell Carcinoma and Adenocarcinoma
75. Renal Pelvis and Ureter: Urothelial Carcinomas
76. Urinary Bladder: Squamous Cell Carcinoma and Adenocarcinoma
77. Urinary Bladder: Urothelial Carcinomas
78. Male Penile and Female Urethra: Squamous Cell Carcinoma and Adenocarcinoma
79. Male Penile and Female Urethra: Urothelial Carcinomas
80. Prostatic Urethra: Squamous Cell Carcinoma and Adenocarcinoma
81. Prostatic Urethra: Urothelial Carcinomas
Part XV: Ophthalmic Sites
82. Eyelid Carcinoma
83. Conjunctival Carcinoma
84. Conjunctival Melanoma
85. Uvea: Choroidal and Ciliary Body Melanomas
86. Uvea: Iris Melanomas
87. Retinoblastoma
88. Lacrimal Gland Carcinoma
89. Orbital Sarcoma
90. Ocular Adnexal Lymphoma
Part XVI: Central Nervous System
91. Brain and Spinal Cord
Part XVII: Endocrine System
92. Thyroid: Differentiated
93. Thyroid: Anaplastic
94. Thyroid: Medullary
95. Parathyroid
96. Adrenal Cortical Carcinoma
97. Adrenal Neuroendocrine Tumors
Part XVIII: Hematologic Malignancies
98. Introduction to Hematologic Malignancies
100. Non-Hodgkin Lymphoma: Mantle Cell Lymphoma
101. Non-Hodgkin Lymphoma: Follicular Lymphoma
102. Non-Hodgkin Lymphoma: Marginal Zone Lymphoma
103. Non-Hodgkin Lymphoma: Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
104. Non-Hodgkin Lymphoma: Peripheral T-Cell Lymphoma
105. Non-Hodgkin Lymphoma: Diffuse Large B-Cell Lymphoma
106. Non-Hodgkin Lymphoma: Not Otherwise Specified
107. Pediatric Hodgkin Lymphomas
108. Pediatric Non-Hodgkin Lymphomas
109. Primary Cutaneous Lymphomas: Mycosis Fungoides and Sezary Syndrome
110. Plasma Cell Myeloma
111. Other Plasma Cell Disorders
112. Leukemia: Acute Myeloid Leukemia
113. Leukemia: Acute Lymphoblastic Leukemia in Children
114. Leukemia: Acute Lymphocytic Leukemia in Adults
115. Leukemia: Chronic Myeloid
116. Leukemia: Unspecified or Other Type
99. Hodgkin Lymphoma
Bibliography
Introduction
Pathology
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