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TNM Cancer Staging System

The TNM Cancer Staging System, 2024 Update, by AJCC is used by physicians and healthcare professionals throughout the world to facilitate the uniform description and reporting of neoplastic diseases. Proper classification and staging of cancer are essential for the physician to assign proper treatment, evaluate results of management and clinical trials, and serve as the standard for local, regional and international reporting on cancer incidence and outcome.

Significantly expanded and developed by international disease site expert panels, this edition features 12 entirely new staging systems, a wide range of changed or new staging definitions, and a refined emphasis on a personalized-medicine approach.

UPDATED CONTENT

  • General staging rules for clinical and pathological classifications
  • Staging systems in several chapters
  • Organization of T, N, M, and any additional categories into groups
  • Histologic classifications and grading systems
  • WHO histology codes
  • More illustrations
  • Extensive update to Version 9 Protocols of
    • Anus
    • Appendix
    • Brain and Spinal Cord
    • Cervix Uteri
    • NET Appendix, Colon and Rectum, Duodenum and Ampulla of Vater, Jejunum and Ileum, Pancreas, Stomach
    • Vulva

NEW PARADIGMS

  • Human papillomavirus (HPV): oropharyngeal carcinoma staging systems based on HPV status
  • Separate staging systems for patients with neoadjuvant therapy (esophagus and stomach)

NEW FEATURES

  • Levels of evidence provided for revisions to staging systems
  • Imaging section
  • Risk Assessment Models for select cancer sites
  • Recommendations for Clinical Trial Stratification
  • Prognostic factors
    • Required for prognostic stage grouping
    • Recommended for clinical care
    • Emerging factors
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