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TNM Cancer Staging Manual
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M1a is defined as lung-only metastases
M1b is all other distant metastasis
M1b is defined as single extrathoracic metastasis in a single organ (including involvement of a single nonregional node)
Major salivary gland s include the parotid, submand ibular, and sublingual gland s
Merkel cell carcinoma in situ (Tis)
M1a is lung metastasis
M1b is defined as metastases to other distant sites, including lymph nodes
M1c includes multiple extrathoracic metastases in a single organ or in multiple organs
Median OS in patients with bone metastases (BM) and other metastases, those without BM, and those with only BM
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