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Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs
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DNA repair
overview
risk and intensity
DNA structure
DNMT
dNTPs
docetaxel, carboplatin, trastuzumab, and pertuzumab (TCHP)
dose-escalation limiting toxicity (DLT)
dose-limiting toxicity (DLT)
DPD
DRESS
DRR
Drug approval and regulatory issues
additional pharmacology considerations
dose refinement studies
drug-drug interaction
food effect
hepatic impairment
INDâchr(128)”enabling nonclinical studies for cancer drugs
QT prolongation
recommended phase 2 dose (RP2D)
renal impairment
Drug developments
clinical trial definitions
clinical trial facts and phases
new active substance launches from 2011 to 2016 by indication
overview
patient selection and study design
protocols
RECIST 1.1, the WHO, and the irRC Criteria
drug reaction with eosinophilia and systemic symptoms (DRESS)
Answer 14.2
Question 14.2
DS
DTIC
dTNP. see deoxyribonucleotide triphosphates (dTNP)
ductal carcinoma in situ (DCIS)
dUMP
DVT
E1
E2
E3
ECM
EFS
EGFR
EKG
electrocardiogram (EKG)
endoplasmic reticulum (ER)
epidermal growth factor receptor (EGFR)
Epigenetic modulators
bromodomain inhibitors
chromatin structure and epigenetic marks
clinical use
overview
treatment goal
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